Description
Price: $75.99 - $33.00
(as of Feb 21, 2025 03:41:01 UTC – Details)
Denamarin coated tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin coated tablets to be safe for dogs. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.
Is Discontinued By Manufacturer : No
Product Dimensions : 5.5 x 3.6 x 1.4 inches; 1.6 ounces
Item model number : DENAMARIN425
Date First Available : January 25, 2008
Manufacturer : Nutramax Laboratories Veterinary Sciences, Inc.
ASIN : B0011XHGR0
Country of Origin : USA
Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione – one of the liver’s main detoxifying agents
High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
Support Your Dog’s Liver Health: The liver is one of the most vital organs in your pet and is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement
Customers say
Customers find the animal nutritional supplement effective and providing good value for money. They say it helps maintain healthy liver function and reduces liver enzyme levels. Many consider it a valuable investment in their pets’ health. However, some customers mention that the pills are large and difficult for their dogs to swallow, making them a mess.
AI-generated from the text of customer reviews
hasselaar –
Excellent Treatment for Older Fur-Kids With Liver Issues.
I foster dogs, but have chosen to specialize in the older and sicker rescued dogs. I have had many, many dogs with liver problems. But for a long time we were losing our precious furry friends, it was awful, there just was not really a very good treatment out there for an old dog with bad liver readings.The problem was that the old dogs all had arthritis, many had been brutalized and abandoned by previous owners, and there were some things that could not be fixed. However, finally we had access to a wide canine assortment of NSAID’s. This was wonderful, the previous only hope was aspirin, with many associated bleeding risks, or dangerous steroids for their poor inflamed, badly healed, and otherwise painful limbs. They were always so good, even though I knew that they were suffering.Then, we suddenly had access to the wonderful mom-steroidal pain relievers. This was magic stuff. Dogs that could barely walk were bouncing around, dogs that could not climb stairs were bounding up, two steps at a time. However, there was a dark side to all of this joy…as we soon discovered. These miracle NSAID’s were pretty rough on the livers of the old dogs. So much so that I was faced with the awful choice of continuing that medication, knowing that it was destroying their liver, but it was also keeping the dogs joints pain-free. My other alternative was no good alternative – no NSAIDS, just heavier and heavier doses of narcotics for the pain……helplessly watching the failing test results of my poor old pups.I lost quite a few that way, it almost killed me. Then Denamarin, and Marin came along. I use both on my old pups and it is another miraculous thing to witness. This is a nom-prescription item that magically lowered bad liver numbers, sometimes within a three or four week period.. It is very expensive, but Amazon has the best price of all.My dogs are living now, and not teetering on the edge with failing livers. It is possible to use NSAID’s in conjunction with Denemarin, and the liver numbers are far better, and the dogs are not doped-up on narcotics, but can enjoy their last days. I am amazed by the breakthroughs that I have witnessed in the veterinary world over the last ten years that I have been fostering. Sometimes it is pretty magical, old dogs frolicking around my ankles each morning, demanding a treat, just like a bunch of pups.I am not a vet., I wish to make that crystal clea. I have no connection whatsoever with this company, indeed had never heard of them before my vet mentioned this drug. All that I can say is that I have had dogs my entire life, and I have witnessed far too many agonizing decisions that have had to be made. Watching an agonized old dog, painfully hobble around, or give the drug that will help with the arthritis…and have very negative effects with their livers. In the.end, we usually just tried to keep them out of pain, but they had.no good quality of life.Again, to be perfectly clear, with MY old dogs, under MY care, eating the very best of dog kibble, no fatty treats, no people food, and someone around at all times to give the drugs at the appropriate times, I have seen rapidly discernible improvement in my older guys. Not every dog reacts the same way, doses can be tricky, and.require a lot of blood testing’ and fiddling with dosages, my dogs have definitely improved. Not all have a glorious outcome. But If they are willing to get out of their beds, and follow me to the kitchen to beg for food, my heart is happy. When you are working with old, injured, and sick dogs…little things matter a lot.Denemarin, along with another supplement : Marin, have made the lives of some of the older fur kids better, and happier. This will not save your old dog, there will be heart problems, cancers, and other issues upon which Denemarin has no effect. But for the dogs in the specific conditions that I have outlined, I have seen a definite difference in both the quality of life for the dog, as well as better liver readings on their blood tests.Again, it is expensive, this makes for a very hard decision for every pet lover. But, it is effective on many dogs. And that is a miracle for me. We are saving dogs that we would have lost ten years ago, and this supplement has had a lot to do with that.It is up to the pet owner, but under the conditions that I have stipulated, this is a worthwhile addition to the supplemental diet of old dogs.
H.C. –
Saved My Dog’s Life
I can’t say enough great things about Denamarin. In August 2014, I had a feeling I should have the vet run blood work on my 11 year old lab mix. She was acting fine, and had no real health issues, it was just a nagging feeling. We ran the blood panel, and it was a good thing we did. ALT is a liver enzyme that is released when there is damage occurring to the liver. A normal ALT value is ideally below 110, my dog’s was 390. Not good, that meant there was some serious liver damage happening. We ran a lot of tests to see what the cause could be. Ultrasound showed nothing abnormal. We did a few rounds of antibiotics in case it was some sort of hepatitis. Nothing really made a difference, and we couldn’t see what the issue was. So we started her on Denamarin. I really didn’t think it would do too much, but I was willing to try. Slowly her ALT values began to lower, I’ll post a little table at the bottom so you can see. By October her ALT was down to 147! Then in November we ran out of Denamarin for a couple weeks. Honestly, I wasn’t too concerned. I assumed she was just getting over whatever had been the issue, I didn’t think the key to her improving was the Denamarin. The next time we measured her ALT in December it was back up to 243. We never ran out of Denamarin again after that, and as of May 2015 her ALT value was 46! Thats right, from a high of 390, down to 46. I could not be happier. Given her age, I did not think that we would be back in the normal range for much. But not only is her ALT back to normal, but so is every blood value they tested. This has been worth every penny. Helpful tip: it is probably a lot cheaper on Amazon than thru the vet. I save $20 a box here.–ALT Values on Denamarin–Aug 2014 390Sept 2014 290Oct 2014 147Dec 2014 243 (this is when we ran out of Denamarin)Jan 2015 114May 2015 46
moonshadow –
Successfully Reduced Liver Values
Just like humans, dogs can have a silent reaction to taking anti-inflammatory prescriptions, so vets tend to order blood tests to measure liver values after a dog has been taking NSAIDs regularly.Sure enough, after a couple months on NSAIDs, our pupâs liver values became elevated, and our vet sent us home with a weekâs worth of Denamarin and instructions to buy more on Amazon. If you buy prescription meds for your pets, you know how pricey the formulations can be, especially for larger dogs. The goal with the first monthâs worth of Denamarin was to stabilize our dogâs liver values and hopefully bring them closer to the normal range. Thus, we were super happy that the first follow-up test showed normal levels. Weâre now tapering off the dosage and hoping for continued good numbers at the next testing period.Giving these pills is simple, as long as youâre good at molding cheese/bread coverings or have pill pockets. Youâll need to remember to give them spaced out, and on an empty stomach. What worked for us was giving the doses an hour before breakfast and dinner. They did not seem to cause any stomach upset.My nitpicks are: the blue dye coating the caplets stains your fingers with the least bit of moisture, and based on my dogâs reaction with a broken pill pocket, the coating probably tastes unpleasant. Also, the caplets are in blister packs for freshness, but it is easy to accidentally pull too hard on the foil backing for one pill and end up exposing a neighboring pill to air. Crimping/perforations like those on sheets of heartworm pills would help. What we ended up doing was cutting each sheet into two-pill strips for each dayâs use.
AJV –
Bandaids on every finger
I think this is a great product for dogs. But be prepared to slice your fingers open and have them throb all night due to the very very sharp metal packaging.
Amazon Customer –
This made such a difference in our dog that has liver enzyme issues. Not sure how it is possible, but she went 4 months Wiiâs seizure while taking this. Before it was 2-3 weeks. She had more energy and basically was a different dog.
NY –
Arrived in a timely manner. My lab/doberman had copper storage disease, diagnosed at 3 years old. The vet gave her 2 weeks. Along with Zinc, homemade food, and distilled water, it seemed to have helped, and I was able to give her 3 more months.
Parsha Lee –
Good price. Fast delivery