Description
Price: $42.99
(as of Feb 16, 2025 04:54:26 UTC – Details)
Denamarin coated tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin coated tablets to be safe for dogs. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.
Is Discontinued By Manufacturer : No
Product Dimensions : 5.6 x 3.6 x 1.4 inches; 1.6 ounces
Item model number : DENAMARIN225
Date First Available : January 25, 2008
Manufacturer : Nutramax Laboratories Veterinary Sciences, Inc.
ASIN : B0011XOXG2
Country of Origin : USA
Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione – one of the liver’s main detoxifying agents
High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs than the standardized milk thistle extract found in many other products
Support Your Dog’s Liver Health: The liver is one of the most vital organs in your pet and is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement
Customers say
Customers find the animal nutritional supplement effective and easy to administer. They say it improves liver function and lowers liver enzyme levels. Many customers are satisfied with the energy level and longevity. However, some dislike the size and have mixed opinions on chewability.
AI-generated from the text of customer reviews
The Sween –
Vetri-Liver and Denamarin is working!!!
Vetri-Liver and Denamarin is working!!!My story: Our dog is a 12ish Jack Russell mix. In August 2017, he was off. Not himself. Bloodwork and ultrasound showed he likely had Chronic Hepatitis. Put him on Denamarin. Bloodwork improved, but still not perfect. Had the vet do a dental thinking that the liver issues could be from bad teeth. They put him on a preventative antibiotic. 1 week after the Dental he spiked a 106 fever. He was ultimately put on IVs with a different antibiotic. Fever came down, felt better. Noticed that he had developed a licking issue after eating which was new. Fever slowly started to climb back upward. At 104 he was put back on IVs, taken off of all antibiotics in an attempt to get the bacteria to flourish and to isolate it. The only problem was that once he was off of the antibiotics his temperature went normal never to return. Eating throughout this has been difficult. Turning down filet mignon or whatever concoction I could come up with to tempt him to eat. I had pointed out to the vets (lots of them) that the antibiotics warned against liver and kidney issues. Everyone poo poo’d that. Well, it turns out that his liver couldn’t process them.I took him home on Christmas Day from the vet hospital. They wanted to do a liver biopsy, but I rejected it. He already looked like warmed over death. Wasn’t eating a thing in the hospital. They would have had to put him back on antibiotics. – And there was no clear indication that the liver was the origin of the problem, and could just be a secondary to another issue like heart disease (he does have a small heart murmur, but his heart is working sufficiently), cancer, etc. Even if we knew exactly what the liver diagnosis was, the treatment wouldn’t be much different: Diet, supplements and potentially prednisone (which is hard on the liver as well – catch 22)At home, he was a new dog. He started eating. I researched every liver diet, and started with a very bland, home-cooked meal. I noticed that if I added a hi-end kibble to his diet, there would be more licking (licking surfaces like the carpeting). I read where compulsive licking is often intestinal distress. I’m not convinced that he also didn’t have some kind of gastric issue, like gastric ulcers, or other intestinal issue, perhaps because of the liver or maybe even driving the liver problem.It is the end of April 2018, and he is doing well. I started him on Vetri-liver in the AM a couple of months ago with a breakfast of eggs, cottage cheese, oatmeal, rice, and chicken/turkey or beef). The Vetri-liver isn’t extremely palatable, but I just cut it in pieces and put it in meat or cheese, and it will go down. Since I don’t have a firm diagnosis for the liver problem, I looked for zinc and anti-oxidants to help the liver even if he had a copper retention problem. Zinc is supposed to offset copper in your diet. It also has some other supplements that he may need.Afternoon, he gets his Denamarin tablet (2 hours after the last meal) and 1 hour before dinner.Supposedly vegetable protein is better for dogs with liver disease. So I came up with some treats that also helped, especially in the beginning when getting him to eat was hard. I fill a turkey pan with: eggs, meat, carrots, sweet potatoes, tofu, wheat germ, peanut butter, coconut oil, and enough oats and a little bit of flour to make a cookie dough. The secret ingredient is a little bacon grease and bacon for palatability. Yes, bad, but makes the difference between this going down the hatch. These can be a mid-day snack, or actually a small meal if we are out hiking, etc. I bake them on cookie tins like brownies, cut them into squares, put them in baggies, and throw them in the freezer. This way they stay fresh.Dinner is rice/oatmeal/sweet potatoes/pumpkin or yams mixed with eggs/chicken/turkey/beef along with some well-processed veggies.I’m not convinced that I’m feeding a balanced diet, so I bought some senior dog vitamins that he gets periodically.Slowly the weight is coming back on. Exercise is important, because he is hungry after exercise. So a small walk in the morning before breakfast and walk before dinner really makes a difference with the pills and food going down. As long as he is eating soft, smaller meals, the compulsive licking has stopped.He is energetic, playing with toys, bright on his walks and back among the living. His liver enzymes are not perfect: ALT started at 275 (August 2017), went to 1,800 during the antibiotic reaction and spiked fever, back to 275 and now down to 253 most recently. ALP started at 263, 656 at its worst, and now at 167. I don’t know if I will be successful in getting them to normal ranges, but if I look at his quality of life, it looks pretty good now.I wanted to share my story, because you don’t hear often that antibiotics could almost kill your dog. And…..your dog can come back after refusing to eat anything after dire illness.Considering a backpack Trip!!
eva –
Cheaper than at the Vet Office
I have 2 dogs taking this: it is cheaper than at the Vet office and delivered to my front door. So far it is helping their liver values.
Customer Review –
Saved my dog when he was at his worst!
Before I review the actual product, I have to complain about the sudden price hike, last week this product was $39 now it’s gone up to $49?? I only bought it on Amazon because it was cheaper than my vet, not anymore! Plus, what’s with the 1 – 2 months before shipping? I’m able to get this at several vets in my area, one sells it for around $40., buying it for the same price with free shipping on Amazon was a simple convenience.Anyway, my dog takes high dose steroids, his liver levels where high among other problems. Medications like steroids and seizure meds will effect the liver function and long term these meds will eventually cause liver failure. An ER vet gave these to him one night and ever since then my dog has been doing great, these really helped him get back to normal! I’ve had his liver function tested several times since he started these and the levels have been perfect with the exception of one slight elevation that is to be expected with steroid use! My dog has a digestive disease and getting his liver and protein level back to normal was very important to help manage his disease, if the levels are not right he is very ill, I feel that these supplements helped my dog get back to normal which in turn helped him to gain back the weight he had lost. I honestly thought he wasn’t going to live more than a month or two, he was looking really bad. I started him on these and stuck with his normal healthy diet and he bounced right back and has stayed that way.Look around though, the prices vary everywhere, I wouldn’t spend more than $40.on them.UPDATE: I see they dropped the price again, back to $37, that’s better. Not sure why the price fluctuates so much! Still would like to be able to get it when I need it though, waiting months isn’t ideal.Another update on price; If you wait a minute the price will either go up or drop. Today I almost ordered some more, tonight the price has gone up again.. several times a day this price is changing, I don’t get it. But watch for $40. that is the average low price but they have been cheaper.
JC –
Best price
Amazon’s price on this medication for my dog is the best I can find in my area.
Valerie –
Needs to be given hidden inside a treat; does help improve liver function (on bloodwork)
My dog has a history of high ALT and ALKP (liver values on bloodwork) from the time she was 5 years old. They were not drastically high, initially; they were just on the high end of normal. When she turned 12 years old, the vet noticed that her liver values had jumped significantly to the point that she was becoming concerned. We did an ultrasound and found that the walls of the liver were thickened, but there was no tumor or anything like that. The vet asked us to try giving her Denamarin to help bring her liver values down. When her bloodwork was rechecked, her ALT was still high, but her ALKP was down, which was exciting! It was still high, but not as high as it was.Unfortunately, when she received her routine wellness bloodwork this month, her ALT has skyrocketed from 188 to over 400. So, my conclusion is the Denamarin did not help this aspect of her liver health. However, her ALKP was still down, so I do think the Denamarin helped with that. We are now going to try adding in a renal support diet along with the Denamarin to see if her bloodwork improves.The pill is large and blue, and I don’t think it tastes good because my dog won’t take it from me by itself as she does with other medications. If I put it inside a Pill Pocket, though, she takes it with no problem.
LeAnn Daniels –
Liver Health
Has kept my Cushingâs Yorkie healthy for years
Janie H. –
Recommended by my vet
My elderly pup takes one every morning. I stopped them for a while and my pup started whining with pain when she walked. Amazon price was a lot less than the vet for the same product. THIS,IS a no brainer specially for an older dog.